AACE ePoster Library

PREVALENCE OF INCIDENTAL ADRENAL ENLARGEMENT ON COMPUTED TOMOGRAPHY (CT) SCAN OF THE ABDOMEN AND SIZE OF ADRENALS IN RELATION TO THE SUBCUTANEOUS VERSUS VISCERAL FAT
AACE ePoster Library. Marchese M. 05/13/15; 97749; 101
Dr. Michael Marchese
Dr. Michael Marchese
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Abstract
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Objective: Adrenal enlargement can be an incidental finding and may be missed during routine reporting. Though its clinical significance is not known at this time, we aimed to evaluate the prevalence of adrenal enlargement on CT abdomen, preliminary to exploring the clinical significance.
Methods: After the approval of the Institutional Review Board, Using the VA computerized patient record system and with the help of the Data Support System, we retrieved the records of Veterans at Stratton VA Medical Center, who had a CT abdomen completed between January 2012 through December 2013. We reviewed all the images of the adrenals in the CT abdomen and measurements were carried out. The clinical information retrieved included age, sex, BMI, presence or absence of obstructive sleep apnea, depression, substance abuse, HTN, malignancy, and medications that alter electrolytes. Adrenal enlargement when present was classified as moderate or severe enlargement.
Results or Case Report: 338 CT scans of the abdomen where reviewed, and 158 records were excluded as they did not meet the criteria. Most of the subjects where men. Subjects with incidentalomas (N=30) reported were not included in the statistical analysis. The mean age of the subjects was 66 ± 13 with mean BMI of 29.5 ± 7.0. Among 50 subjects with adrenal enlargement, 39 subjects had bilateral enlargement and 11 had unilateral enlargement. The prevalence of adrenal enlargement was 14.8%. Only 11 (22%) of the 50 adrenal enlargements were reported. Subjects with incidental adrenal enlargement had a higher prevalence of hypertension (p <0.001) and electrolyte abnormalities (p <0.001). Adrenal enlargement positively correlated with BMI (r = 0.17; p <0.01), visceral fat (r = 0.15; p <0.01), and subcutaneous fat (r = 0.19; p <0.01).
Conclusion: Since adrenal enlargement is more common in those with higher BMI, hypertension and electrolyte abnormalities, and correlates with both visceral and subcutaneous fat, it may be worth studying the benefit of hormonal evaluation to explore clinical relevance.
Objective: Adrenal enlargement can be an incidental finding and may be missed during routine reporting. Though its clinical significance is not known at this time, we aimed to evaluate the prevalence of adrenal enlargement on CT abdomen, preliminary to exploring the clinical significance.
Methods: After the approval of the Institutional Review Board, Using the VA computerized patient record system and with the help of the Data Support System, we retrieved the records of Veterans at Stratton VA Medical Center, who had a CT abdomen completed between January 2012 through December 2013. We reviewed all the images of the adrenals in the CT abdomen and measurements were carried out. The clinical information retrieved included age, sex, BMI, presence or absence of obstructive sleep apnea, depression, substance abuse, HTN, malignancy, and medications that alter electrolytes. Adrenal enlargement when present was classified as moderate or severe enlargement.
Results or Case Report: 338 CT scans of the abdomen where reviewed, and 158 records were excluded as they did not meet the criteria. Most of the subjects where men. Subjects with incidentalomas (N=30) reported were not included in the statistical analysis. The mean age of the subjects was 66 ± 13 with mean BMI of 29.5 ± 7.0. Among 50 subjects with adrenal enlargement, 39 subjects had bilateral enlargement and 11 had unilateral enlargement. The prevalence of adrenal enlargement was 14.8%. Only 11 (22%) of the 50 adrenal enlargements were reported. Subjects with incidental adrenal enlargement had a higher prevalence of hypertension (p <0.001) and electrolyte abnormalities (p <0.001). Adrenal enlargement positively correlated with BMI (r = 0.17; p <0.01), visceral fat (r = 0.15; p <0.01), and subcutaneous fat (r = 0.19; p <0.01).
Conclusion: Since adrenal enlargement is more common in those with higher BMI, hypertension and electrolyte abnormalities, and correlates with both visceral and subcutaneous fat, it may be worth studying the benefit of hormonal evaluation to explore clinical relevance.

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